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11α-Hydroxy canrenone lulú (192569-17-8)

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SKU: 192569-17-8. Ẹka:

AASraw wa pẹlu iṣelọpọ ati agbara iṣelọpọ lati gram si aṣẹ pupọ ti 11α-Hydroxy canrenone Powder (192569-17-8), labẹ ilana CGMP ati eto iṣakoso didara didara.

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11α-Hydroxy canrenone Powder (192569-17-8) fidio


11α-Hydroxy canrenone lulú (192569-17-8) Specification:

Ẹya Kẹmika: ọja orukọ:11α-Hydroxy canrenone
Raw 11α-Hydroxy canrenone lulú (192569-17-8) hplc≥98% | AASraw CAS No.: 192569-17-8
molikula agbekalẹ: C22H28O4
molikula iwuwo: 356.46
Synonyms: 11-Alpha-Hydroxycarvenone
Ibi: Gbẹ, ṣokunkun · ati ni 0 - 4 C fun igba kukuru (awọn ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (awọn oṣu si ọdun).
Awọn iwe aṣẹ (COA & HPLC ati bẹbẹ lọ): wa

11α-Hydroxy canrenone lulú (192569-17-8) Dorukọ:

11α-Hydroxy canrenone ṣiṣẹ kanna bi Canrenone jẹ antagonist aldosterone pẹlu iṣẹ diuretic potasiomu. Canrenone pataki antagonizes aldosterone ni olugba mineralocorticoid ninu awọn kidinrin, nitorinaa npo iṣuu soda ati didi iyọkuro potasẹ.Canrenone jẹ irohin agbara diẹ bi alafaramo antimineralocorticoid si spironolactone, ṣugbọn ni agbara pupọ ati pe o munadoko bi antiandrogen.11α-ọlọla sitẹriọdu ati ti iṣelọpọ ti progesterone.It jẹ antiandrogen ti ko lagbara, ati pe ko ni aibikita ati androgenic, estrogenic, ati iṣẹ ṣiṣe progestogenic

Reference:

  • Jürg Müller (6 Oṣu kejila ọdun 2012). Ilana Aldosterone Biosynthesis: Ti ẹkọ-iṣe ati imọ-ara ile-iwosan. Orisun omi Imọ-jinlẹ & Media. Oju ewe 164-. ISBN 978-3-642-83120-1.
  • Ford, Donald H. (1954). “AGBARA TI 11α-HYDROXYPROGESTERONE LATI IBI Iṣeduro TI NIPA TI A NIPA TI RẸ NI ỌJỌ ỌJỌ ỌJỌ RẸ *”. Iwe akosile ti Clinical Endocrinology & Ti iṣelọpọ. 14 (10): 1268–1270. doi: 10.1210 / jcem-14-10-1268. ISSN 0021-972X.
  • Souness GW, Latif SA, Laurenzo JL, Morris DJ (1995). “11 alfa- ati 11 beta-hydroxyprogesterone, awọn idiwọ agbara ti 11 beta-hydroxysteroid dehydrogenase (isoforms 1 ati 2), confer samisi iṣẹ mineralocorticoid lori corticosterone ninu eku ADX”. Endocrinology. 136 (4): 1809-12.