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Nicotinamide riboside kiloraidi

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Ọja Apejuwe

Awọn Abuda Ipilẹ

ọja orukọ Nicotinamide riboside kiloraidi
CAS Number 23111-00-4
molikula agbekalẹ C11H15ClN2O5
Ilana iwuwo 290.7
Awọn Synonyms 23111-00-4

Nicotinamide riboside kiloraidi

Nicotinamide riboside (kiloraidi)

3-Carbamoyl-1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride

Nicotinamide ribose kiloraidi

irisi White lulú
Ifipamọ ati mimu 0 - 4 C fun igba kukuru (awọn ọjọ si awọn ọsẹ), tabi -20 C fun igba pipẹ (awọn oṣu).

 

Nicotinamide riboside kiloraidi Apejuwe

Nicotinamide Riboside Chloride (NIAGEN) jẹ ẹya iyọ ti kiloraidi ti nicotinamide riboside (NR) .NR jẹ fọọmu tuntun pyridine-nucleoside ti Vitamin B3 eyiti o ṣiṣẹ bi ipilẹṣẹ si nicotinamide adenine dinucleotide (NAD) tabi NAD + .NIAGEN ni gbogbogbo mọ bi ailewu (GRAS) ni Amẹrika fun lilo ninu awọn ọja onjẹ. Nicotinamide riboside kiloraidi jẹ ọna kirisita ti Nicotinamide riboside (NR) kiloraidi. Nicotinamide riboside kiloraidi mu awọn ipele NAD [+] wa ati mu SIRT1 ati SIRT3 ṣiṣẹ, ni ipari ni iṣelọpọ ti iṣelọpọ ti a mu dara si ati aabo lodi si awọn ohun ajeji ti iṣelọpọ ti ounjẹ ti ọra ti o ga julọ. A lo Nicotinamide riboside kiloraidi lulú ninu awọn afikun awọn ounjẹ.

 

Nicotinamide riboside kiloraidi Ilana ti Ise

Nicotinamide Riboside Chloride (NIAGEN) jẹ iyọ iyọ ti kiloraidi ti nicotinamide riboside (NR). NR jẹ fọọmu pyridine-nucleoside ti Vitamin B3 ti n ṣiṣẹ bi iṣaaju si adinini dinucleotide nicotinamide tabi NAD +. Awọn ohun amorindun NR ti ibajẹ ti awọn eegun ganglion gbongbo ti iṣẹ abẹ ti abẹ ex vivo ati aabo fun pipadanu igbọran ti ariwo ninu awọn eku laaye. Nicotinamide riboside lulú ṣe idiwọ iṣan, nkankikan ati imọlara sẹẹli sẹẹli melanocyte. Alekun iṣan ti iṣan ni awọn eku ti ṣe akiyesi lẹhin itọju pẹlu nicotinamide riboside, ti o yori si akiyesi pe o le mu atunṣe ti awọn ẹya bii ẹdọ, iwe, ati ọkan. Nicotinamide riboside tun dinku glukosi ẹjẹ ati ẹdọ ọra ni prediabetic ati iru awọn awoṣe ọgbẹ suga 2 lakoko idilọwọ idagbasoke idagbasoke ti neuropathy agbeegbe ti ọgbẹgbẹ. Akiyesi: Nicotinamide Riboside kiloraidi jẹ adalu α / β.

 

Nicotinamide riboside kiloraidi Ohun elo

Nicotinamide riboside kiloraidi lulú ti wa ni aami-pẹlu nọmba CAS 23111‐00‐4 ati nọmba EC 807‐820‐5. Orukọ IUPAC rẹ ni 1 - [(2R, 3R, 4S, 5R) ‐3,4 ‐ dihydroxy ‐ 5‐ (hydroxymethyl) oxolan ‐ 2 ‐ yl] pyridin ‐ 1 ‐ ium ‐ 3 ‐ carboxamide; kiloraidi. Agbekalẹ molikula ti nicotinamide riboside kiloraidi jẹ C11H15N2O5Cl, ati iwuwo molikula rẹ 290.7 g / mol. Nicotinamide Riboside Chloride (NIAGEN) jẹ iyọ iyọ ti kiloraidi ti nicotinamide riboside (NR) .NR jẹ fọọmu tuntun pyridine-nucleoside ti Vitamin B3 eyiti o ṣiṣẹ bi ipilẹṣẹ si nicotinamide adenine dinucleotide (NAD) tabi NAD +. Ara nilo NAD + lati ṣiṣẹ ni deede. Awọn ipele kekere ti NAD + le fa awọn iṣoro iṣoogun. Gbigba riboside nicotinamide le ṣe iranlọwọ lati gbe awọn ipele NAD + kekere wọnyi.

 

anfani ti Nicotinamide riboside kiloraidi

Nicotinamide riboside Chloride, iṣaaju NAD + iṣaaju, n mu awọn ipele NAD + pọ si ati mu SIRT1 ati SIRT3 ṣiṣẹ. Nicotinamide riboside Chloride lulú jẹ orisun ti Vitamin B3 (niacin) ati lo Nicotinamide riboside Chloride lulú le mu iṣelọpọ ti iṣelọpọ ṣiṣẹ, aabo lodi si awọn ohun ajeji ti iṣelọpọ ti ounjẹ ti o sanra pupọ. Nicotinamide riboside Chloride dinku ibajẹ imọ ninu awoṣe asin transgenic kan ti aisan Alzheimer.

 

Reference

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