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Mometasone furoate (83919-23-7)

Rating: SKU: 83919-23-7. Ẹka:

AASraw wa pẹlu iṣelọpọ ati agbara iṣelọpọ lati gram si aṣẹ pupọ ti Mometasone furoate (83919-23-7), labẹ ilana CGMP ati eto iṣakoso didara didara.

Ọja Apejuwe

Mometasone furoate (83919-23-7) fidio


Mometasone furoate (83919-23-7) Specification:

Ẹya Kẹmika: ọja orukọ: Mometasone furoate
CAS No.: 83919-23-7
molikula agbekalẹ: C27H30Cl2O6
molikula iwuwo: 521.4
Synonyms:mometasone furoate

83919-23-7

Nasonex

Asmanex

Elocon

Ibi: Gbẹ, dudu
Awọn iwe aṣẹ (COA & HPLC ati bẹbẹ lọ): wa

Mometasone furoate (83919-23-7) Dorukọ:

Furoate Mometasone jẹ furo iyọ iyọda ti mometasone, agonist igigirisẹ glucocorticosteroid pẹlu alamọ-iredodo, awọn ohun-ini alatako ati awọn ohun-ini vasoconstrictive.

Mometasone furoate ṣe ipa ipa rẹ nipa abuda si awọn olugba cytoplasmic glucocorticoid ati tẹle iṣẹ mu olugba glucocorticoid ti n ṣalaye ikosile pupọ pupọ. Eyi ni abajade ninu kolaginni ti awọn ọlọjẹ alatako iredodo, lakoko ti o ṣe idiwọ kolaginni ti awọn olulaja iredodo kan.

Ni pataki, mometasone furoate han lati ṣe ifilọlẹ awọn ọlọjẹ inhibitory phospholipase A2, nitorinaa o nṣakoso itusilẹ ti ara iwaju arachidonic acid lati sẹfufu phospholipid nipasẹ phospholipase A2.

Reference:

  • 1: Zalmanovici Trestioreanu A, awọn sitẹriọdu amúṣantóbi ti Yaphe J. Intranasal fun sinusitis ńlá. Cochrane aaye data Syst Rev. 2013 Oṣu keji 2; 12: CD005149. doi: 10.1002 / 14651858.CD005149.pub4. Atunwo. PubMed PMID: 24293353.
  • 2: Ellis AK, North ML, Walker T, Steacy LM. Ẹyọ ifihan ti agbegbe: imọlara kan, pato, ati ilana ẹda ti ipilẹ fun ipenija allergen. Ann Allergy Asthma Immunol. Oṣu kọkanla 2013; 111 (5): 323-8. doi: 10.1016 / j.anai.2013.07.019. Atunwo. PubIDed PMID: 24125135.
  • 3: Lee JT, Han JK. Awọn iṣan inu iṣan fun awọn rhinosinusitis onibaje: igbelewọn imọ-ẹrọ. Onimọran Opin Oògùn Deliv. Oṣu Kẹwa ọdun 2013; 10 (12): 1735-48. doi: 10.1517 / 17425247.2013.839654. Epub 2013 Oṣu Kẹwa 3. Atunwo. PubIDed PMID: 24088141.
  • 4: Nannini LJ, Poole P, Milan SJ, Kesterton A. Iṣakojọpọ corticosteroid ati beta (anesitetiki) gigun (2) -agonist ninu ifasimu kan si inhaled corticosteroids nikan fun arun onibaje ẹkun inu. Cochrane aaye data Syst Rev. 2013 Oṣu Kẹjọ 30; 8: CD006826. doi: 10.1002 / 14651858.CD006826.pub2. Atunwo. PubIDed PMID: 23990350.

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